At one time oxandrolone was considered as a possible drug for those suffering from disorders of high cholesterol or triglycerides. Early studies showed it to be capable of lowering total cholesterol and triglyceride values in certain types of hyperlipidemic patients. Initially, this was thought to signify potential for this drug as a hypo-lipid (lipid lowering) agent. Further investigation found that while use of this drug can be linked to a lowering of total cholesterol valu es, it comprises a redistribution in the ratio of good (HDL) to bad (LDL) cholesterol, usually moving values in an unfavorable direction. This negates any positive effect that the drug might have on triglycerides or total cholesterol, and in fact makes it a dangerous choice in terms of cardiac risk when taken for prolonged periods of time. Today we understand that as a group, anabolic/androgenic steroids produce very unfavorable changes in lipid profiles, and are not useful in disorders of lipid metabolism.